How will I receive Yervoy?

You will get Yervoy through an intravenous line in your vein (infusion). It takes about 90 minutes to get a full dose.

Yervoy is usually given every 3 weeks for up to 4 doses. Your healthcare provider may change how often you receive Yervoy or how long the infusion may take.
Your healthcare provider should perform blood tests before starting and during treatment with Yervoy.
It is important for you to keep all appointments with your healthcare provider. Call your healthcare provider if you miss an appointment. There may be special instructions for you.

What are the possible side effects of Yervoy?

Yervoy can cause serious side effects. See “What is the most important information I should know about Yervoy?”

The most common side effects of Yervoy include:
tiredness
diarrhea
itching
rash
These are not all of the possible side effects of Yervoy. For more information, ask your healthcare provider.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Bristol-Myers Squibb at 1-800-721-5072.

General information about the safe and effective use of Yervoy.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.

This Medication Guide summarizes the most important information about Yervoy. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider for information about Yervoy that is written for healthcare professionals.

For more information, call 1-800-321-1335.

What are the ingredients of Yervoy?

Active ingredient: ipilimumab

Inactive ingredients: diethylene triamine pentaacetic acid (DTPA), mannitol, polysorbate 80, sodium chloride, tris hydrochloride, and Water for Injection, USP

This Medication Guide has been approved by the U.S. Food and Drug Administration.
Manufactured by:
Bristol-Myers Squibb Company
Princeton, NJ 08543 USA
U.S. License No. 1713

1281558A4
1281915A3
Rev May 2013
---------------------------------------------
REPRESENTATIVE PACKAGING
See How Supplied section for a complete list of available packages of Yervoy.
NDC 0003-2327-11
Rx only
Yervoy®
(ipilimumab)
Injection
50 mg/10 mL
(5 mg/mL)
For Intravenous Infusion Only
Single-use vial; Discard unused portion
DISPENSE ENCLOSED MEDICATION GUIDE TO EACH PATIENT
Bristol-Myers Squibb

NDC 0003-2328-22
Rx only
Yervoy®
(ipilimumab)
Injection
200 mg/40 mL
(5 mg/mL)
For Intravenous Infusion Only
Single-use vial; Discard unused portion
DISPENSE ENCLOSED MEDICATION GUIDE TO EACH PATIENT
Bristol-Myers Squibb

Yervoy
ipilimumab injection
Product Information
Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0003-2327
Route of Administration INTRAVENOUS DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
IPILIMUMAB (IPILIMUMAB) IPILIMUMAB 5 mg  in 1 mL
Inactive Ingredients
Ingredient Name Strength
TROMETHAMINE HYDROCHLORIDE 3.15 mg  in 1 mL
SODIUM CHLORIDE 5.85 mg  in 1 mL
MANNITOL 10 mg  in 1 mL