Before you take INLYTA, tell your doctor if you:
 • have high blood pressure
 • have thyroid problems
 • have liver problems
 • have a history of blood clots in your veins or arteries (types of blood vessels), including stroke, heart attack, or change in vision
 • have any bleeding problems
 • have an unhealed wound
• plan to have surgery. You should stop taking INLYTA at least 24 hours before planned surgery.
 • have any other medical conditions
 
For females, tell your doctor if you:
•are pregnant or plan to become pregnant. Taking INLYTA during pregnancy may cause the death of an unborn baby or birth defects. You should not become pregnant while taking INLYTA. Talk to your doctor if you are pregnant or plan to become pregnant.
•are able to become pregnant. You should use effective birth control during your treatment with INLYTA. Talk to your doctor about birth control methods to prevent pregnancy while you are taking INLYTA.
 •are breastfeeding or plan to breastfeed. It is not known if INLYTA passes into your breast milk. You and your doctor should decide if you will take INLYTA or breastfeed. You should not do both.
For males:
•use effective birth control during your treatment with INLYTA. Talk to your doctor about birth control methods.
 •if your female partner becomes pregnant while you are taking INLYTA, tell your doctor right away.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. INLYTA and certain other medicines can affect each other causing serious side effects.
 
Especially tell your doctor if you take:
 • dexamethasone
 • St. John's Wort (Hypericum perforatum)
 • Medicine for:
◦asthma
◦tuberculosis
◦seizures
◦bacterial infections
◦fungal infections
◦depression
◦HIV or AIDS
Ask your doctor or pharmacist if you are not sure if your medicine is one listed above. If you are taking any medicines for the conditions listed above, your doctor might need to prescribe a different medicine or your dose of INLYTA may need to be changed. Talk with your doctor before you start taking any new medicine.
 
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
 
How should I take INLYTA?
• Take INLYTA exactly as prescribed by your doctor.
 • Your doctor may change your dose if needed.
 • INLYTA can be taken with or without food.
 • Take INLYTA 2 times a day approximately 12 hours apart.
 • Swallow INLYTA tablets whole with a glass of water.
 • Your doctor should check your blood pressure regularly during treatment with INLYTA.
 • If you vomit or miss a dose of INLYTA, take your next dose at your regular time. Do not take two doses at the same time.
 •If you take too much INLYTA, call your doctor or go to the nearest hospital emergency room right away.