Visit your doctor or health care professional for regular checks on your progress. Learn how to check your blood sugar. Tell your doctor or health care professional if your blood sugar is high, you might need to change the dose of your medicine.

If you are sick or exercising more than usual, you might need to change the dose of your medicine. Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol.

If you have symptoms of low blood sugar, eat or drink something containing sugar at once and contact your doctor or health care professional.

Make sure family members know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, like seizures or unconsciousness. They must get medical help at once.

Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.
What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
dark urine
dizziness
feeling faint or lightheaded, falls
fever, chills, sore throat
low blood sugar (ask your doctor or healthcare professional for a list of these symptoms)
muscle aches, pains
slow or irregular heartbeat
stomach pain
swelling of the hands, legs, or feet
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

diarrhea
headache
stomach gas, heartburn
nausea
problems with teeth
This list may not describe all possible side effects.
Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

FDA批准ACTOplus met(R) XR片剂用于治疗2型糖尿病
美通社-PR Newswire5月13日伊利诺伊州迪尔菲尔德和日本大阪电　Takeda Pharmaceutical Company Limited 及其全资子公司 Takeda Pharmaceuticals North America, Inc. 今天宣布，美国食品和药物管理局 (U.S. Food and Drug Administration, FDA) 已批准将缓释型组合药物 ACTOplus met(R)(盐酸匹格列酮 (pioglitazone HCl) 和盐酸二甲双胍 (metformin HCl))作为治疗2型糖尿病的一种饮食和锻炼辅助剂。ACTOplus met(R) XR 是首款也是唯一一款带有二甲双胍缓释剂的抗糖尿病固定剂量口服组合药物，旨在通过每天一次的方便的剂量选择帮助改善血糖控制。ACTOplus met XR 用于对已经采用 ACTOS(R)(盐酸匹格列酮)和二甲双胍治疗的进行治疗，或者单独采用 ACTOS 或二甲双胍治疗而不足以控制血糖的2型糖尿病成年患者。
ACTOplus met XR 将两种广泛使用的药物 ACTOS 和二甲双胍结合到一个药片上。ACTOS 直接针对胰岛素抵抗。胰岛素抵抗是一种身体不能有效使用身体产生的胰岛素的疾病。二甲双胍通过减少肝脏产生的葡萄糖的数量起作用。这些药物联合发挥作用，帮助2型糖尿病患者管理他们的血糖水平