1.Swallow Creon capsules whole and take them with enough liquid to swallow them right away.
2.If you have trouble swallowing capsules, open the capsules and sprinkle the contents on a small amount of room temperature acidic food such as applesauce. Ask your doctor about other foods you can mix with Creon.
3.If you sprinkle Creon on food, swallow it right after you mix it and drink enough water or juice to make sure the medicine is swallowed completely. Do not store Creon that is mixed with food.
4.If you forget to take Creon, call your doctor or wait until your next meal and take your usual number of capsules. Take your next dose at your usual time. Do not make up for missed doses.
What are the possible side effects of Creon?

Creon may cause serious side effects, including:

•See “ What is the most important information I should know about Creon? ”
•Irritation of the inside of your mouth. This can happen if Creon is not swallowed completely.
•Increase in blood uric acid levels. This may cause worsening of swollen, painful joints (gout) caused by an increase in your blood uric acid levels.
•Allergic reactions, including trouble with breathing, skin rashes, or swollen lips.
Call your doctor right away if you have any of these symptoms.

The most common side effects of Creon include:

•Blood sugar increase (hyperglycemia) or decrease (hypoglycemia)
•Pain in your stomach (abdominal area)
•Frequent or abnormal bowel movements
•Gas
•Vomiting
•Dizziness
•Sore throat and cough
Other Possible Side Effects:

Creon and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the side effects of Creon. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

You may also report side effects to AbbVie Inc. at 1-800-633-9110.

How should I store Creon?

•Store Creon at room temperature below 77°F (25°C). Avoid heat.
•You may store Creon at a temperature between 77°F to 104°F (25°C to 40°C) for up to 30 days. Throw away any Creon stored at these temperatures for more than 30 days.
•Keep Creon in a dry place and in the original container.
•After opening the bottle, keep it closed tightly between uses to protect from moisture.
Keep Creon and all medicines out of the reach of children.

General information about Creon

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use Creon for a condition for which it was not prescribed. Do not give Creon to other people to take, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about Creon. If you would like more information, talk to your doctor. You can ask