hance of having a rare bowel disorder called fibrosing colonopathy. This condition is serious and may require surgery. The risk of having this condition may be reduced by following the dosing instructions that your doctor gave you. Call your doctor right away if you have any unusual or severe:
•stomach area (abdominal) pain
•bloating
•trouble passing stool (having bowel movements)
•nausea, vomiting, or diarrhea
Take Creon exactly as prescribed. Do not take more or less Creon than directed by your doctor.
What is Creon?
Creon is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions. Creon may help your body use fats, proteins, and sugars from food.
Creon contains a mixture of digestive enzymes including lipases, proteases, and amylases from pig pancreas.
What should I tell my doctor before taking Creon?
Before taking Creon, tell your doctor about all your medical conditions, including if you:
•are allergic to pork (pig) products
•have a history of intestinal blockage of your intestines, or scarring or thickening of your bowel wall (fibrosing colonopathy)
•have gout, kidney disease, or high blood uric acid (hyperuricemia)
•have trouble swallowing capsules
•have any other medical condition
•are pregnant or plan to become pregnant. It is not known if Creon will harm your unborn baby.
•are breast-feeding or plan to breast-feed. It is not known if Creon passes into your breast milk.
Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine.
How should I take Creon?
•Take Creon exactly as your doctor tells you.
•You should not switch Creon with any other pancreatic enzyme product without first talking to your doctor.
•Do not take more capsules in a day than the number your doctor tells you to take (total daily dose).
•Always take Creon with a meal or snack and enough liquid to swallow Creon completely. If you eat a lot of meals or snacks in a day, be careful not to go over your total daily dose.
•Your doctor may change your dose based on the amount of fatty foods you eat or based on your weight.
•Do not crush or chew Creon capsules or its contents, and do not hold the capsule or capsule contents in your mouth. Crushing, chewing or holding the Creon capsules in your mouth may cause irritation in your mouth or change the way Creon works in your body.
Giving Creon to infants (children up to 12 months)
1.Give Creon right before each feeding of formula or breast milk.
2.Do not mix Creon capsule contents directly into formula or breast milk.
3.Open the capsules and sprinkle the contents directly into your infant's mouth or mix the contents in a small amount of room temperature acidic soft food such as applesauce. These foods should be the kind found in baby food jars that you buy at the store, or other food recommended by your doctor.
4.If you sprinkle the Creon on food, give the Creon and food mixture to your child right away. Do not store Creon that is mixed with food.
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