umira with your doctor or nurse so that you are not startled by this click when you start giving yourself the injections at home.
◦The loud click sound means the start of the injection.
◦You will know that the injection has finished when the yellow marker appears fully in the window view and stops moving.
See the section below called “Prepare the Humira Pen”.
How should I store Humira?
•Store Humira in a refrigerator at 36ºF to 46ºF (2ºC to 8ºC) in the original container until it is used. Protect from light.
•When traveling, Humira should be stored in a cool carrier with an ice pack.
•Do not freeze Humira. Do not use Humira if frozen, even if it has been thawed.
•Refrigerated Humira may be used until the expiration date printed on the Humira carton, dose tray, and Pen.
•Do not use a Pen if the liquid is cloudy, discolored, or has flakes or particles in it.
•Do not drop or crush Humira.
•Keep Humira, injection supplies, and all other medicines out of the reach of children.
Gather the Supplies for Your Injection
•You will need the following supplies for your injection of Humira.
Find a clean, flat surface to place the supplies on.
◦1 alcohol swab
◦1 cotton ball or gauze pad (not included in your Humira carton)
◦1 Humira Pen (See Figure A)
◦1 FDA-cleared sharps disposal container for Humira Pen disposal (not included in your Humira carton)
If you do not have all of the supplies you need to give yourself an injection, go to a pharmacy or call your pharmacist. The diagram below shows what the Humira Pen looks like. See Figure A.
Figure A
Check the carton, dose tray, and Humira Pen.
1. Make sure the name Humira appears on the carton, dose tray, and Humira Pen label.
2. Do not use and call your doctor or pharmacist if:
•you drop or crush your Humira Pen.
•the seals on the top or bottom of the carton are broken or missing.
•the expiration date on the carton, dose tray, and Pen has passed.
•the Humira Pen has been frozen or left in direct sunlight. See the section: “How should I store Humira?” at the beginning of these Instructions For Use.
3. Hold the Pen with the gray cap (Cap # 1) pointed down.
4. Make sure the amount of liquid in the Pen is at the fill line or close to the fill line seen through the window. This is the full dose of Humira that you will inject. See Figure B.
5. If the Pen does not have the full amount of liquid, do not use that Pen. Call your pharmacist.
Figure B
6. Turn the Pen over and hold the Pen with the gray cap (Cap # 1) pointed up. See Figure C.
7. Check the solution through the windows on the side of the Pen to make sure the liquid is clear and colorless. Do not use your Humira Pen if the liquid is cloudy, discolored, or if it has flakes or particles in it. Call your pharmacist. It is normal to see one or more bubbles in the window.
Figure C
Choose the Injection Site
8. Wash and dry your hands well.
9. Choose an injection site on:
•the front of your thighs or
•your lower abdomen (belly). If you choose your abdomen, do not use the area 2 inches around your belly button (navel). See Figure D.
Figure D
•Choose a different site each time you give yourself an injection. Each new injection should be given at least one inch from a site you used before.
•Do not inject Humira into skin that is:
◦sore (tender)
◦bruised
◦red
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