y skin reactions occur [see Warnings and Precautions (5.3)].
Tumor Lysis Syndrome
Inform patients about the risk of and the signs and symptoms of tumor lysis syndrome. Patients should be instructed to notify their physician if they experience these symptoms [see Warnings and Precautions (5.4)].
Concomitant Medications
Patients should be instructed to inform their physician if they are taking any concomitant medications including prescription drugs (such as trimethoprim/sulfamethoxazole) and nonprescription drugs (such as nonsteroidal anti-inflammatory drugs) [see Drug Interactions (7)].
Pregnancy/Nursing
Patients should be instructed to tell their physician if they are pregnant or plan to become pregnant due to the risk of fetal harm. Patients should be instructed to tell their physician if they are nursing.
ALLOS®
THERAPEUTICS
Manufactured for:
Allos Therapeutics, Inc.
Westminster, CO 80020
1-888-ALLOS88 (1-888-255-6788)
Folotyn, ALLOS, and the mobius triangle symbol are all registered trademarks of Allos Therapeutics, Inc.
U.S. Patents: 6,028,071 and 7,622,470
Rev. 7: May 2012
© 2012 Allos Therapeutics, Inc. All rights reserved.
Patient Information
Folotyn®(FOH-loh-tin)
(pralatrexate injection)
Read the Patient Information that comes with Folotyn before you start treatment and each time you get treated with Folotyn. There may be new information. This leaflet does not take the place of talking to your doctor about your medical condition or treatment. Talk to your doctor if you have any questions about Folotyn.
What is Folotyn?
Folotyn is a prescription anti-cancer (chemotherapy) medicine. Folotyn is used to treat people with a type of cancer called Peripheral T-cell Lymphoma (PTCL) that does not go away, gets worse, or comes back after use of another cancer treatment.
What should I tell my doctor before receiving Folotyn?
Before you receive Folotyn, tell your doctor if you:
•have liver problems.
•have kidney problems.
•have any other medical conditions.
•are pregnant or plan to become pregnant. Folotyn can harm your unborn baby. Talk to your doctor about the best way to prevent pregnancy while taking Folotyn. Tell your doctor right away if you become pregnant while taking Folotyn.
•are breast-feeding or plan to breast-feed. It is not known if Folotyn passes into breast milk. You and your doctor should decide if you will take Folotyn or breast-feed. You should not do both. Talk to your doctor about the best way to feed your baby while you are being treated with Folotyn.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Folotyn works, and Folotyn may affect how other medicines works. Especially tell your doctor if you take:
•sulfamethoxazole trimethoprim (Bactrim®, Septra®, Septra DS, Sulfatrim Pediatric, Sulfamethoprim, Sulfamethoprim-DS)
•non-steroidal anti-inflammatory drugs (NSAIDs)
•probenecid (Probalan, Col-Probenecid)
Ask your doctor or pharmacist if you are not sure if your medicine is listed above.
icines you take. Keep a list of them and show it to your doctor or pharmacist each time you start a new medicine.
How will I receive Folotyn?
•Folotyn will be given to you as directed by your doctor, as an intravenous (IV) injection into your vein over 3 to 5 minutes.
•Folotyn is us |
