vir. Efavirenz and fosamprenavir can cause a decrease in the Noxafil levels in your body. Efavirenz and fosamprenavir should not be taken with Noxafil.
•are taking midazolam, a hypnotic and sedative medicine.
•have or had liver problems.
•have or had kidney problems.
•have or had an abnormal heart rate or rhythm, heart problems, or blood circulation problems.
•are pregnant or plan to become pregnant. It is not known if Noxafil will harm your unborn baby.
•are breastfeeding or plan to breastfeed. It is not known if Noxafil passes into your breast milk. You and your healthcare provider should decide if you will take Noxafil or breastfeed. You should not do both.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you take:
•rifabutin or phenytoin. If you are taking these medicines, you should not take Noxafil delayed-release tablets or Noxafil oral suspension.
•cimetidine or esomeprazole. If you are taking these medicines, you should not take Noxafil oral suspension.
Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure.
Know the medicines you take. Keep a list of them with you to show your healthcare provider or pharmacist when you get a new medicine.
How should I take Noxafil?
•Take Noxafil exactly as your healthcare provider tells you to take it.
•Your healthcare provider will tell you how much Noxafil to take and when to take it.
•Take Noxafil for as long as your healthcare provider tells you to take it.
•If you take too much Noxafil, call your healthcare provider or go to the nearest hospital emergency room right away.
• Noxafil Delayed-Release Tablets: ◦Take Noxafil delayed-release tablets with food.
◦Take Noxafil delayed-release tablets whole. Do not break, crush, dissolve or chew Noxafil delayed-release tablets before swallowing. If you cannot swallow Noxafil delayed-release tablets whole, tell your healthcare provider. You may need a different medicine.
◦If you miss a dose, take it as soon as you remember and then take your next scheduled dose at its regular time. If, however, it is within 12 hours of your next dose, do not take the missed dose. Skip the missed dose and go back to your regular schedule. Do not double your next dose or take more than your prescribed dose.
• Noxafil Oral Suspension: ◦Shake Noxafil oral suspension well before use.
◦Take each dose of Noxafil oral suspension during or within 20 minutes after a full meal. If you cannot eat a full meal, take each dose of Noxafil oral suspension with a liquid nutritional supplement or an acidic carbonated beverage, like ginger ale.
◦A measured dosing spoon comes with your Noxafil oral suspension and is marked for doses of 2.5 mL and 5 mL. See Figure A.
Image of Figure 1
Figure A
◦Rinse the spoon with water after each dose of Noxafil oral suspension and before you store it away |
