4a.
Hold the syringe (like a pencil) at a 45-degree angle to the skin. With a quick "dart-like" motion, push the needle into the skin.

FOR INTRAMUSCULAR INJECTION:

4b.
Hold the syringe (like a pencil) at a 90-degree angle to the skin. With a quick "dart-like" motion, push the needle into the muscle.

5.
After the needle is in, remove the hand used to pinch the skin and use it to hold the syringe barrel. Pull the plunger back slightly. If blood comes into the syringe, the needle has entered a blood vessel. Do not inject INTRON® A. Withdraw the needle and discard the syringe in the puncture-proof container. See "How should I dispose of materials used to inject INTRON A?") Prepare a new dose of INTRON A and prepare a new injection site.
6.
If no blood is present in the syringe, inject the medicine by gently pushing the plunger all the way down until the syringe is empty.
7.
When the syringe is empty, pull the needle out of the skin and place a cotton ball or gauze over the injection site and press for several seconds. Do not massage the injection site. If there is bleeding, cover the injection site with a bandage.
8.
Dispose of syringe and needle. See "How should I dispose of materials used to inject INTRON A?"
9.
If after using a multidose vial (18 million IU or 25 million IU) there is enough solution left in the vial for another dose, refrigerate the INTRON A vial after use. Discard any unused INTRON A solution remaining after one month.
10.
It is important to check your injection site approximately two hours after your injection for redness, swelling, or tenderness. These are signs of inflammation that you may need to talk to your healthcare provider about if they do not go away.
How should I dispose of materials used to inject INTRON® A?

There may be special state and local laws for disposal of used needles and syringes. Your healthcare provider should provide you with instructions on how to properly dispose of your used syringes and needles. Always follow those instructions. The instructions below should be used as a general guide for proper disposal.

The needles and syringes should never be reused.
Place all used needles and syringes in a puncture-proof disposable container that is available through your pharmacy or healthcare provider. You may also use a hard plastic container with a screw-on cap (like a laundry detergent container).
Do not use glass or clear plastic containers for disposal of needles and syringes.
The container used for the disposal of syringes and needles should be clearly labeled as "USED SYRINGES AND NEEDLES." When the container is almost full, tighten the lid. Tape the cap or lid to make sure it does not come off. Dispose of the container as instructed by your healthcare provider.
DO NOT throw the container in your household trash and DO NOT recycle.
Always keep the container out of reach of children
Schering Corporation Kenilworth, NJ 07033 USA

Copyright © 1996, 2001, 2004, Schering Corporation. All rights reserved.

U.S. Patent No. 5,935,566 and 6,610,830.

Rev. 8/09

B-XXXXXXXX

277777XXT

PRINCIPAL DISPLAY PANEL - Single-Use Vial Label
SCHERING

NDC 0085-0571-02

Interferon alfa-2b,
recombinant

In