are pregnant, planning to get pregnant, or breast-feeding
are a male patient on combination therapy and have a female sexual partner who is pregnant or plans to become pregnant while you are being treated with REBETOL or during the 6 months after your treatment has ended
have autoimmune hepatitis (hepatitis caused by your immune system attacking your liver) or unstable liver disease (yellowing of the skin and eyes, swelling of the abdomen)
had an allergic reaction to another alpha interferon or ribavirin or are allergic to any of the ingredients in INTRON A or REBETOL
If you have any of the following conditions or serious medical problems, tell your healthcare provider before taking INTRON A alone or in combination with REBETOL:

depression or anxiety
eye problems
sleep problems
high blood pressure
previous heart attack, or other heart problems
liver problems (other than hepatitis B or C)
any kind of autoimmune disease (where the body's immune system attacks the body's own cells), such as psoriasis, sarcoidosis, systemic lupus erythematosus, rheumatoid arthritis
thyroid problems
diabetes
colitis (inflammation of the bowels)
cancer
hepatitis B or C infection
HIV infection (the virus that causes AIDS)
kidney problems
bleeding problems
alcoholism
drug abuse or addiction
body organ transplant and are taking medicine that keeps your body from rejecting your transplant (suppresses your immune system)
high blood triglycerides (fat particles normally found in your blood)
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. INTRON A and certain other medicines may affect each other and cause side effects.

Especially tell your doctor if you take the anti-hepatitis B medicine telbivudine (Tyzeka). See "What are the possible side effects of INTRON A?"

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

How should I take INTRON® A?

To get the most benefit from this medicine, it is important that you take INTRON A exactly as your healthcare provider tells you. Your healthcare provider will decide your dose of INTRON A and how often you will take it. Do not take more than your prescribed dose. INTRON A is given as an injection either under the skin (subcutaneous) or into a muscle (intramuscular). You should be completely comfortable with how to prepare and measure your dose of INTRON A and how to inject yourself before you use INTRON A for the first time. Your healthcare provider will train you on how to use and inject INTRON A properly.

INTRON A comes in different strengths and different forms (a powder in a vial, a solution in a vial, and a multidose pen). Your healthcare provider will determine which form is best for you. The instructions for giving a dose of INTRON A are at the end of this leaflet.

If you miss a dose of INTRON A, take the missed dose as soon as possible during the same day or the next day, then continue on your regular dosing schedule. If several days go by after you miss a dose, check with your healthcare provider to see what to do. Do not double your next dose or take more than your prescribed dose without talking to your healthcare provider. Call your healthcare provider right away if you take more than your prescribed dose. Your healthcare provider may wish to examine you more closely an