Keep the needle in the vial and turn the vial upside down. Make sure the tip of the needle is in the DILUENT. Slowly pull the plunger back to fill the syringe with DILUENT to the number (mL or cc) that your healthcare provider instructed you to use.

With the needle still inserted in the vial, check the syringe for air bubbles. If there are any air bubbles, gently tap the syringe with your finger until the air bubbles rise to the top of the syringe. Slowly push the plunger up to remove the air bubbles. If you push DILUENT back into the vial, slowly pull back on the plunger to again draw the correct amount of DILUENT back into the syringe.

Remove the needle from the vial. Do not let the syringe touch anything.
Without touching the cleaned rubber stopper, insert the needle through the middle of the rubber stopper and gently place the needle tip, at an angle, against the side of the INTRON A powder vial.
Slowly push the plunger down to inject the DILUENT. The stream of liquid should run down the sides of the glass vial. DO NOT INJECT THE DILUENT DIRECTLY AT THE WHITE POWDER.

Do not remove the needle from the vial.
To dissolve the white powder, gently swirl the INTRON A vial in a circular motion until the powder is completely dissolved. DO NOT SHAKE. If the solution is foamy, wait a few minutes until the bubbles have settled before withdrawing your dose from the vial.

Check the solution inside the vial of the INTRON A. The solution should be clear and colorless to light yellow, without particles. Do not use the INTRON A if the medicine is cloudy, has particles or is any color besides clear and colorless to light yellow.
With the needle in the vial, turn the vial upside down. Make sure the tip of the needle is in the INTRON A solution. Slowly pull the plunger back to fill the syringe with the INTRON A solution to the number (mL or cc) that your healthcare provider has prescribed.

With the needle still inserted in the vial, check the syringe for air bubbles. If there are any air bubbles, gently tap the syringe with your finger until the air bubbles rise to the top of the syringe.

Slowly push the plunger up to remove the air bubbles. If you push solution back into the vial, slowly pull back on the plunger again to draw the correct amount of INTRON A solution back into the syringe.
Do not remove the needle from the vial. Lay the vial and syringe on its side on your flat work surface until you are ready to inject the INTRON A solution.

Choosing an Injection site

Based on your treatment, your health care provider will tell you if you should inject a dose of INTRON® A subcutaneously (under the skin) or intramuscularly (into the muscle). If it is too difficult for you to inject, ask someone who has been trained to give injections to help you.

FOR SUBCUTANEOUS INJECTION

The best sites for injection are areas on your body with a layer of fat between skin and muscle such as:

the front of your middle thighs
the outer area of your upper arms
the abdomen, except around the navel

FOR INTRAMUSCULAR INJECTION

The best sites for injection into your muscle are:

the front of the middle thighs
the upper arms
the upper outer areas of the buttocks

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