INTRON A Solution for Injection, 6 doses of 10 million IU (60 million IU) Multidose Pen (75 million IU per 1.5 mL per pen); boxes containing 1 INTRON A Multidose Pen, six disposable needles and alcohol swabs (NDC 0085-1254-01).

INTRON A Solution for Injection in Vials
INTRON A Solution for Injection, 18 million IU multidose vial (22.8 million IU per 3.8 mL per vial); boxes containing 1 vial of INTRON A Solution for Injection (NDC 0085-1168-01).

INTRON A Solution for Injection, 25 million IU multidose vial (32 million IU per 3.2 mL per vial); boxes containing 1 vial of INTRON A Solution for Injection (NDC 0085-1133-01).

Storage
INTRON A Powder for Injection/Reconstitution
INTRON A Powder for Injection should be stored at 2° to 8°C (36°–46°F). After reconstitution, the solution should be used immediately, but may be stored up to 24 hours at 2°–8°C (36°–46°F).
INTRON A Solution for Injection in Vials
INTRON A Solution for Injection in Vials should be stored at 2°–8°C (36°–46°F).
INTRON A Solution for Injection in Multidose Pens
INTRON A Solution for Injection in Multidose Pens should be stored at 2°–8°C (36°–46°F).

References
Smalley R, et al. N Engl J Med. 1992;327:1336–1341.
Aviles A, et al. Leukemia and Lymphoma. 1996;20:495–499.
Unterhalt M, et al. Blood. 1996;88:(10 Suppl 1):1744A.
Schiller J, et al. J.Biol Response Mod. 1989;8:252–261.
Poynard T, et al. N Engl J Med. 1995;332:(22)1457–1462.
Lin R, et al. J Hepatol. 1995;23:487–496.
Perrillo R, et al. N Engl J Med. 1990;323:295–301.
Perez V, et al. J Hepatol. 1990;11:S113–S117.
Knodell R, et al. Hepatology. 1981;1:431–435.
Perrillo R, et al. Ann Intern Med. 1991;115:113–115.
Renault P, et al. Arch Intern Med. 1987;147:1577–1580.
Kauppila A, et al. Int J Cancer. 1982;29:291–294.

Manufactured by Schering Corporation, a subsidiary of Schering-Plough Corporation, Kenilworth, NJ 07033 USA.

Rev. 07/09
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© 1986, 2008, Schering Corporation. All rights reserved.
US Patent Nos. 5,935,566 and 6,610,830

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MEDICATION GUIDE
INTRON® A
(Interferon alfa-2b, recombinant)

Including appendix with instructions for using INTRON A Multidose Pen for Injection

Read this Medication Guide carefully before you start to take INTRON A (In-tron aye) for Injection alone or INTRON A in combination with REBETOL® (REB-eh-tole) (ribavirin, USP) Capsules. Read the Medication Guide each time you refill your prescription because there may be new information. The information in this Medication Guide does not take the place of talking with your healthcare provider.

If you are taking INTRON A and REBETOL combination therapy, also read the Medication Guide for REBETOL (ribavirin, USP) Capsules.

What is the most important information I should know about INTRON® A?

INTRON A is a treatment for some people who have hairy cell leukemia, malignant melanoma, follicular lymphoma, AIDS-related Kaposi's sarcoma, chronic hepatitis B, chronic hepatitis C, and condylomata acuminata. If you have chronic hepatitis C, your h