How should I take ZELBORAF?

Take ZELBORAF exactly as your healthcare provider tells you. Do not change your dose or stop ZELBORAF unless your healthcare provider tells you.
ZELBORAF is taken in the morning and in the evening, about 12 hours apart.
Take ZELBORAF with or without a meal.
Swallow the tablets whole with a glass of water. Do not chew or crush ZELBORAF tablets.
If you miss a dose, take it as soon as you remember. If it is within 4 hours of your next scheduled dose, just take your next dose at your regular time. Do not make up for the missed dose.
Do not take 2 doses of ZELBORAF at the same time.
If you take too much ZELBORAF, call your healthcare provider right away.
What should I avoid while taking ZELBORAF?

Avoid sunlight while you are taking ZELBORAF. ZELBORAF can make your skin sensitive to sunlight. You may burn more easily and get severe sunburns. To help protect against sunburn:

When you go outside, wear clothes that protect your skin, including head, face, hands, arms, and legs.
Use lip balm and a broad-spectrum sunscreen with SPF 30 or higher.
What are the possible side effects of ZELBORAF?

ZELBORAF may cause serious side effects, including:

See "What is the most important information I should know about ZELBORAF?"
Allergic reactions can happen while taking your ZELBORAF, and may be severe. Stop taking ZELBORAF and get medical help right away if you have any of these symptoms of an allergic reaction: get a rash or redness all over your body
feel faint
have trouble breathing or swallowing
 have throat tightness or hoarseness
have a fast heartbeat
have swelling of the face, lips or tongue

Severe skin reactions. Stop taking ZELBORAF and call your healthcare provider right away if you get a skin rash with any of the following symptoms because you may have a severe skin reaction:

blisters on your skin
blisters or sores in your mouth
peeling of your skin
 fever
redness or swelling of your face, hands, or soles of your feet
Changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life-threatening. Your healthcare provider should do tests before you start taking ZELBORAF, if your dose changes, at certain other times during treatment, and after you stop treatment with ZELBORAF, to check the levels of potassium, magnesium, and calcium in your blood, and check the electrical activity of your heart with an ECG.
Tell your healthcare provider right away if you feel faint, lightheaded, dizzy or feel your heart beating irregularly or fast whil